4-bromo-3-(4H-1,2,4-triazol-3-yl)thiophen-2-amine → N-(4-Bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(6-ethynyl-2-oxoquinolin-1(2H)-yl)acetamide
Reaction equation
[Br:18][c:19]1[c:20](-[c:25]2[n:26][cH:27][n:28][nH:29]2)[c:21]([NH2:24])[s:22][cH:23]1.[C:1](#[CH:2])[c:3]1[cH:4][c:5]2[cH:6][cH:7][c:8](=[O:17])[n:9]([CH2:13][C:14](=[O:15])[OH:16])[c:10]2[cH:11][cH:12]1>>[C:1](#[CH:2])[c:3]1[cH:4][c:5]2[cH:6][cH:7][c:8](=[O:17])[n:9]([CH2:13][C:14](=[O:16])[NH:24][c:21]3[c:20](-[c:25]4[n:26][cH:27][n:28][nH:29]4)[c:19]([Br:18])[cH:23][s:22]3)[c:10]2[cH:11][cH:12]1Participants
3
Sources & evidence
- ORD record
- ord-b972777a85144425904fbf3789f99d81
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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