Potassium Cation → 4-chloro-3-(6-chloro-4-methyl-pyridin-3-yl)-N-(2-hydroxy-phenyl)-N-methyl-benzamide

HRID 298373

Reaction equation

HRID 298373 reaction equation
[Br:28][c:29]1[c:30]([CH3:36])[cH:31][c:32]([Cl:35])[n:33][cH:34]1.[Cl:1][c:2]1[c:3]([B:19]2[O:20][C:21]([CH3:22])([CH3:23])[C:24]([CH3:25])([CH3:26])[O:27]2)[cH:4][c:5]([C:6](=[O:7])[N:8]([CH3:9])[c:10]2[c:11]([OH:16])[cH:12][cH:13][cH:14][cH:15]2)[cH:17][cH:18]1.[K+:37].[K+:38].[O-:39][C:40]([O-:41])=[O:42].[O:43]1[CH2:44][CH2:45][O:46][CH2:47][CH2:48]1.[cH:49]1[cH:50][cH:51][c:52]([P:53]([Pd:54]([P:55]([c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)([c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)[c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)([P:74]([c:75]2[cH:76][cH:77][cH:78][cH:79][cH:80]2)([c:81]2[cH:82][cH:83][cH:84][cH:85][cH:86]2)[c:87]2[cH:88][cH:89][cH:90][cH:91][cH:92]2)[P:93]([c:94]2[cH:95][cH:96][cH:97][cH:98][cH:99]2)([c:100]2[cH:101][cH:102][cH:103][cH:104][cH:105]2)[c:106]2[cH:107][cH:108][cH:109][cH:110][cH:111]2)([c:112]2[cH:113][cH:114][cH:115][cH:116][cH:117]2)[c:118]2[cH:119][cH:120][cH:121][cH:122][cH:123]2)[cH:124][cH:125]1>>[Cl:1][c:2]1[c:3](-[c:29]2[c:30]([CH3:36])[cH:31][c:32]([Cl:35])[n:33][cH:34]2)[cH:4][c:5]([C:6](=[O:7])[N:8]([CH3:9])[c:10]2[c:11]([OH:16])[cH:12][cH:13][cH:14][cH:15]2)[cH:17][cH:18]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 27344275-Bromo-2-chloro-4-methylpyridineHCID 686030284-chloro-N-(2-hydroxy-phenyl)-N-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzamideHCID 178420554HCID 178420554, compound

Product 1

HCID 866425714-chloro-3-(6-chloro-4-methyl-pyridin-3-yl)-N-(2-hydroxy-phenyl)-N-methyl-benzamide

Sources & evidence

ORD record
ord-6764aeba127f4f5685496b98ff149e94
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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