Ethyl benzoylacetate → HCID 178515559, compound

HRID 29890

Reaction equation

HRID 29890 reaction equation
C(O[C:4](=[O:14])[CH2:5][C:6](=O)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)C.Cl.[C:16]([NH2:24])(=[NH:23])[C:17]1[CH:22]=[CH:21][N:20]=[CH:19][CH:18]=1>>[C:7]1([C:6]2[N:24]=[C:16]([C:17]3[CH:22]=[CH:21][N:20]=[CH:19][CH:18]=3)[N:23]=[C:4]([OH:14])[CH:5]=2)[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 7170Ethyl benzoylacetateHCID 2776844Pyridine-4-amidine hydrochloride

Product 1

HCID 178515559HCID 178515559, compound

Procedure

The title compound was prepared from 3-oxo-3-phenyl-propionic acid ethyl ester and isonicotinamidine hydrochloride according to general procedure 1. 1H NMR (DMSO-d6, 400 MHz) δ 7.08 (s, 1H), 7.50-7.55 (m, 3H), 8.17-8.25 (m, 4 H), 8.88 (d, J=4.4 Hz, 2H), 10-12 (br s, 1H); MS: m/z(ESI) 250 (M+H).

Sources & evidence

ORD record
ord-655cf54f8f9d44f997d89b4fd30052d6
Source dataset
uspto-grants-2008_09
Patent number
US07423044B2

Linked notes

Loading…