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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 29900Generated: October 26, 2026

4-Fluorobenzyl bromide → 2-(4-Chlorophenyl)-4-[(4-fluorobenzyl)oxy]-6-phenylpyrimidine

https://huagongshe.com/reaction/29900

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzyl bromideHCID 68021—
ReactantHCID 178515558HCID 178515558—
Product2-(4-Chlorophenyl)-4-[(4-fluorobenzyl)oxy]-6-phenylpyrimidineHCID 10363010—

Reaction Steps

The title compound was prepared from 2-(4-chloro-phenyl)-6-phenyl-pyrimidin-4-ol (which was obtained in Intermediate 1) and 4-fluorobenzyl bromide according to Method A; LC retention time 4.35 min; MS: m/z (ESI) 391 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07423044B2
Source datasetuspto-grants-2008_09
ORD IDord-230f657d8e3d4a6a8770b3ebd44fd36b
Source noteuspto-grants-2008_09