Potassium Cation → 2-[2-(4-isopropyl-1-piperidinyl)ethyl]-1H-isoindole-1,3(2H)-dione

Reaction equation

[Br:10][CH2:11][CH2:12][N:13]1[C:14](=[O:23])[c:15]2[c:16]([cH:19][cH:20][cH:21][cH:22]2)[C:17]1=[O:18].[C:24](=[O:25])([O-:26])[O-:27].[CH3:30][C:31]#[N:32].[CH:1]([CH3:2])([CH3:3])[CH:4]1[CH2:5][CH2:6][NH:7][CH2:8][CH2:9]1.[K+:28].[K+:29]>>[CH:1]([CH3:2])([CH3:3])[CH:4]1[CH2:5][CH2:6][N:7]([CH2:11][CH2:12][N:13]2[C:14](=[O:23])[c:15]3[c:16]([cH:19][cH:20][cH:21][cH:22]3)[C:17]2=[O:18])[CH2:8][CH2:9]1

Participants

Reactant 5

HCID 813Potassium Cation2×

HCID 6342Acetonitrile

HCID 113251H-Isoindole-1,3(2H)-dione, 2-(2-bromoethyl)-

HCID 19660Carbonate Ion

HCID 140569Piperidine, 4-(1-methylethyl)-

Product 1

HCID 219782572-[2-(4-isopropyl-1-piperidinyl)ethyl]-1H-isoindole-1,3(2H)-dione

Sources & evidence

ORD record: ord-347966b148334e8ca8c79652e7d7c9d9
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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