1-Benzyl-4-piperidylamine → N-(1-benzylpiperidin-4-yl)-7-methoxy-4-(5-methylthiophen-2-yl)phthalazin-1-amine
Reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([O:12][CH3:13])[CH:10]=2)[C:5]([C:14]2[S:15][C:16]([CH3:19])=[CH:17][CH:18]=2)=[N:4][N:3]=1.[NH2:20][CH:21]1[CH2:26][CH2:25][N:24]([CH2:27][C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[CH2:23][CH2:22]1>>[CH2:27]([N:24]1[CH2:25][CH2:26][CH:21]([NH:20][C:2]2[C:11]3[C:6](=[CH:7][CH:8]=[C:9]([O:12][CH3:13])[CH:10]=3)[C:5]([C:14]3[S:15][C:16]([CH3:19])=[CH:17][CH:18]=3)=[N:4][N:3]=2)[CH2:22][CH2:23]1)[C:28]1[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=1Participants
3
Procedure
This compound is obtained according to the procedure described in 1.4. by reacting 1-chloro-7-methoxy-4-(5-methylthiophen-2-yl)phthalazine with 4-amino-1-benzylpiperidine.
Workup
- customThis compound is obtained
Sources & evidence
- ORD record
- ord-ecd619d2bb514c7381c728f3797674d9