Propionyl chloride → 3,5-Dimethoxy-2-propionylbenzoic acid

HRID 29970

Reaction equation

HRID 29970 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:10]=[C:11]([O:13][CH3:14])[CH:12]=1)[C:6]([O:8]C)=[O:7].[C:15](Cl)(=[O:18])[CH2:16][CH3:17]>>[CH3:1][O:2][C:3]1[C:4]([C:15](=[O:18])[CH2:16][CH3:17])=[C:5]([CH:10]=[C:11]([O:13][CH3:14])[CH:12]=1)[C:6]([OH:8])=[O:7]

Participants

3

Reactant 2

HCID 62324Propionyl chlorideHCID 75074Methyl 3,5-Dimethoxybenzoate

Product 1

HCID 692142953,5-Dimethoxy-2-propionylbenzoic acid

Procedure

This compound is synthesized by reacting methyl 3,5-dimethoxybenzoate with propionyl chloride via the Friedel-Crafts reaction, followed by saponification of the ester obtained, according to the method described in 2.1. It is used in crude form in the following reaction.

Workup

  1. customThis compound is synthesized
  2. customvia the Friedel-Crafts reaction
  3. customobtained
  4. customin the following reaction

Sources & evidence

ORD record
ord-9378b4ce2200480e812cad8e537d91d2
Source dataset
uspto-grants-2008_09
Patent number
US07423030B2

Linked notes

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