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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 29986Generated: October 27, 2026

2-Bromo-5-methoxybenzoic acid → 2-(4-Chlorobenzoyl)-5-methoxybenzoic acid

https://huagongshe.com/reaction/29986

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-5-methoxybenzoic acidHCID 89906—
Reactant4-Chloro-N-methoxy-N-methylbenzamideHCID 11275663—
ReactantButyllithiumHCID 178418339—
Product2-(4-Chlorobenzoyl)-5-methoxybenzoic acidHCID 69213277—

Reaction Steps

This compound is synthesized according to the method described in 3.2. by reacting 2-bromo-5-methoxybenzoic acid pretreated with n-butyllithium with 4-chloro-N-methoxy-N-methylbenzamide. It is used in crude form in the following reaction.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07423030B2
Source datasetuspto-grants-2008_09
ORD IDord-d55504ac77cd4e53af8c9e2bb4deec01
Source noteuspto-grants-2008_09