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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 300883Generated: October 27, 2026

Hydrochloric Acid → N-((1RS,2SR)-2-(4-fluorophenyl)-2-hydroxy-1-((4-(trifluoromethyl)phenyl)methyl)ethyl)-6-(methyloxy)-1-naphthalenecarboxamide

https://huagongshe.com/reaction/300883

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
ReactantOxalyl chlorideHCID 65578—
Reactant6-Methoxy-1-naphthoic acidHCID 4413708—
Reactant(1RS,2RS)-1-(4-fluorophenyl)-1-hydroxy-3-(4-(trifluoromethyl)phenyl)-2-propylamineHCID 22261479—
ProductN-((1RS,2SR)-2-(4-fluorophenyl)-2-hydroxy-1-((4-(trifluoromethyl)phenyl)methyl)ethyl)-6-(methyloxy)-1-naphthalenecarboxamideHCID 22261895—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-5a7b2c421bae45069b6b55aa9349f54b
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)