HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-2-fluoro-4-iodo-5-methoxybenzene → (2-Amino-6-chloro-pyridin-3-yl)-(4-chloro-5-fluoro-2-methoxy-phenyl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-2-fluoro-4-iodo-5-methoxybenzene | HCID 21070630 | — |
| Reactant | 2-Amino-6-chloro-N-methoxy-N-methyl-nicotinamide | HCID 58590824 | — |
| Product | (2-Amino-6-chloro-pyridin-3-yl)-(4-chloro-5-fluoro-2-methoxy-phenyl)-methanone | HCID 58590823 | — |
Reaction Steps
The title compound was prepared from 2-Amino-6-chloro-N-methoxy-N-methyl-nicotinamide (Example 3) and 5-chloro-4-fluoro-2-iodoanisole (prepared as described in Step A above) using the procedure described in Example 7. HRMS, observed: 312.9943, Calcd for (M−H)+: 312.9947.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07423051B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-8b2ab23d421d4ca7b820de3c492a45e2 |
| Source note | uspto-grants-2008_09 |