3H-spiro(isobenzofuran-1,4'-piperidin)-3-one → 1'-[(1-Benzyl-2-methyl-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one

HRID 304512

Reaction equation

HRID 304512 reaction equation
[CH2:16]([c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1)[n:23]1[c:24]([CH3:35])[c:25]([C:32](=[O:33])[OH:34])[c:26]2[cH:27][cH:28][cH:29][cH:30][c:31]12.[NH:1]1[CH2:2][CH2:3][C:4]2([O:5][C:6](=[O:13])[c:7]3[c:8]2[cH:9][cH:10][cH:11][cH:12]3)[CH2:14][CH2:15]1>>[N:1]1([C:32]([c:25]2[c:24]([CH3:35])[n:23]([CH2:16][c:17]3[cH:18][cH:19][cH:20][cH:21][cH:22]3)[c:31]3[c:26]2[cH:27][cH:28][cH:29][cH:30]3)=[O:33])[CH2:2][CH2:3][C:4]2([O:5][C:6](=[O:13])[c:7]3[c:8]2[cH:9][cH:10][cH:11][cH:12]3)[CH2:14][CH2:15]1

Participants

3

Reactant 2

HCID 98342553H-spiro(isobenzofuran-1,4'-piperidin)-3-oneHCID 667434811-Benzyl-2-methyl-1H-indole-3-carboxylic acid

Product 1

HCID 159527101'-[(1-Benzyl-2-methyl-1H-indol-3-yl)carbonyl]-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one

Sources & evidence

ORD record
ord-584a6417e78e484485347518780b3433
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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