2-Amino-4-methyl-thiazole-5-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide → 5-(3-Chloro-4-trifluoromethyl-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid [5-(2-hydroxy-1,1-dimethyl-ethylsulfamoyl)-4-methyl-thiazol-2-yl]-amide

Reaction equation

[Cl:1][c:2]1[cH:3][c:4](-[c:12]2[n:13][c:14]3[n:15]([c:16]([C:18]([F:19])([F:20])[F:21])[cH:17]2)[n:22][cH:23][c:24]3[C:25](=[O:26])[OH:27])[cH:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11].[OH:28][CH2:29][C:30]([CH3:31])([CH3:32])[NH:33][S:34](=[O:35])(=[O:36])[c:37]1[c:38]([CH3:43])[n:39][c:40]([NH2:42])[s:41]1>>[Cl:1][c:2]1[cH:3][c:4](-[c:12]2[n:13][c:14]3[n:15]([c:16]([C:18]([F:19])([F:20])[F:21])[cH:17]2)[n:22][cH:23][c:24]3[C:25](=[O:26])[NH:42][c:40]2[n:39][c:38]([CH3:43])[c:37]([S:34]([NH:33][C:30]([CH2:29][OH:28])([CH3:31])[CH3:32])(=[O:35])=[O:36])[s:41]2)[cH:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11]