2-(Bromomethyl)tetrahydro-2H-pyran → N-Benzyl-4-methyl-2-(2-oxo-4-((tetrahydro-2H-pyran-2-yl)methoxy)pyridin-1(2H)-yl)thiazole-5-carboxamide
Reaction equation
[Br:1][CH2:2][CH:3]1[O:4][CH2:5][CH2:6][CH2:7][CH2:8]1.[CH2:9]([c:10]1[cH:11][cH:12][cH:13][cH:14][cH:15]1)[NH:16][C:17](=[O:18])[c:19]1[c:20]([CH3:32])[n:21][c:22](-[n:24]2[c:25](=[O:31])[cH:26][c:27]([OH:30])[cH:28][cH:29]2)[s:23]1>>[CH2:2]([CH:3]1[O:4][CH2:5][CH2:6][CH2:7][CH2:8]1)[O:30][c:27]1[cH:26][c:25](=[O:31])[n:24](-[c:22]2[n:21][c:20]([CH3:32])[c:19]([C:17]([NH:16][CH2:9][c:10]3[cH:11][cH:12][cH:13][cH:14][cH:15]3)=[O:18])[s:23]2)[cH:29][cH:28]1Participants
3
Sources & evidence
- ORD record
- ord-029632e80fc9406b93321a891178aa6d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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