Dichloromethane → 2-Fluoromethyl-5-methyl-2,3,6,7-tetrahydrofuro-[2,3-f]quinoline-7-one

HRID 307220

Reaction equation

HRID 307220 reaction equation
[CH2:18]([N:19]([S:20]([F:21])([F:22])[F:24])[CH2:23][CH3:25])[CH3:26].[CH2:27]([Cl:28])[Cl:29].[OH:1][CH2:2][CH:3]1[CH2:4][c:5]2[c:6]([c:7]3[cH:8][cH:9][c:10](=[O:16])[nH:11][c:12]3[c:13]([CH3:15])[cH:14]2)[O:17]1>>[CH2:2]([CH:3]1[CH2:4][c:5]2[c:6]([c:7]3[cH:8][cH:9][c:10](=[O:16])[nH:11][c:12]3[c:13]([CH3:15])[cH:14]2)[O:17]1)[F:24]

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 123472(Diethylamino)sulfur trifluorideHCID 233696792-Hydroxymethyl-5-methyl-2,3,6,7-tetrahydrofuro[2,3-f]quinoline-7-one

Product 1

HCID 233697882-Fluoromethyl-5-methyl-2,3,6,7-tetrahydrofuro-[2,3-f]quinoline-7-one

Sources & evidence

ORD record
ord-3755382469e9454eaabd0062a64ada89
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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