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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 3075Generated: October 26, 2026

1-Bromo-3,5-difluorobenzene → 3(3,5-Difluorophenyl)thiophene

https://huagongshe.com/reaction/3075

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-3,5-difluorobenzeneHCID 136313—
Reactant1-Bromo-3,4,5-trifluorobenzeneHCID 611409—
Reactant3-(3,4,5-Trifluorophenyl)thiopheneHCID 23295528—
Product3(3,5-Difluorophenyl)thiopheneHCID 22743691—

Reaction Steps

The same procedures set forth above in Example (1)(a) for synthesizing 3(3,4,5-trifluorophenyl)thiophene were followed, with the exception that 1-bromo-3,5-difluorobenzene was substituted for 1-bromo-3,4,5-trifluorobenzene as the 1-bromo-substituted fluorobenzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05733683
Source datasetuspto-grants-1998_03
ORD IDord-1353d03acc334b3781453676e9c404d0
Source noteuspto-grants-1998_03