Acetone → 5-(7-Bromo-heptyloxy)-1-(4-fluoro-phenyl)-1H-indole

Reaction equation

[Br:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][Br:32].[CH3:33][C:34](=[O:35])[CH3:36].[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[cH:9][cH:10][c:11]3[cH:12][c:13]([OH:17])[cH:14][cH:15][c:16]23)[cH:6][cH:7]1.[K+:18].[K+:19].[O-:20][C:21]([O-:22])=[O:23]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[cH:9][cH:10][c:11]3[cH:12][c:13]([O:17][CH2:31][CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][CH2:25][Br:24])[cH:14][cH:15][c:16]23)[cH:6][cH:7]1

Participants

Reactant 5

HCID 180Acetone

HCID 813Potassium Cation2×

HCID 19660Carbonate Ion

HCID 783091,7-Dibromoheptane

HCID 114815561-(4-Fluoro-phenyl)-1H-indol-5-ol

Product 1

HCID 186795565-(7-Bromo-heptyloxy)-1-(4-fluoro-phenyl)-1H-indole

Sources & evidence

ORD record: ord-e4fa00885c094e1b84f59142e79abc1c
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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