HuagongsheHuagongshe Chemistry Print Report · For research reference only
Monoethyl malonate → N-[(S)-5-(2-Benzyloxy-ethyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-malonamic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Monoethyl malonate | HCID 70615 | — |
| Reactant | (S)-7-amino-5-(2-benzyloxy-ethyl)-5H,7H-dibenzo[b,d]azepin-6-one | HCID 58972512 | — |
| Product | N-[(S)-5-(2-Benzyloxy-ethyl)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-malonamic acid ethyl ester | HCID 58972492 | — |
Reaction Steps
Using (S)-7-amino-5-(2-benzyloxy-ethyl)-5H,7H-dibenzo[b,d]azepin-6-one and malonic acid monoethyl ester, the title compound was prepared in the same manner as described for example 1c. Colorless oil (>98%). MS: m/e=473(M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07425551B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-2c6ee7b8c12a4f92a9adf5eea3e07444 |
| Source note | uspto-grants-2008_09 |