Bicarbonate Ion → 1'-allyl-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one

HRID 310598

Reaction equation

[C:16](=[O:17])([OH:18])[O-:19].[CH2:21]([CH:22]=[CH2:23])[Br:24].[CH:25]([Cl:26])([Cl:27])[Cl:28].[NH:1]1[CH2:2][CH2:3][C:4]2([O:5][C:6](=[O:13])[c:7]3[cH:8][cH:9][cH:10][cH:11][c:12]32)[CH2:14][CH2:15]1.[Na+:20]>>[N:1]1([CH2:23][CH:22]=[CH2:21])[CH2:2][CH2:3][C:4]2([O:5][C:6](=[O:13])[c:7]3[cH:8][cH:9][cH:10][cH:11][c:12]32)[CH2:14][CH2:15]1

Participants

Reactant 5

HCID 769Bicarbonate Ion

HCID 923Sodium ion

HCID 6212Chloroform

HCID 7841Allyl bromide

HCID 98342553H-spiro(isobenzofuran-1,4'-piperidin)-3-one

Product 1

HCID 215068211'-allyl-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one

Sources & evidence

ORD record: ord-59b542a1fbfe4366856eabf768361df3
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Linked notes

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