Diethyl Ether → tert-Butyl 4-(5-(hydroxy(thiophen-2-yl)methyl)-[1,2,4]triazolo[4,3-a]pyrazin-8-yl)piperazine-1-carboxylate
Reaction equation
[CH2:6]([O:7][CH2:8][CH3:9])[CH3:10].[CH3:11][CH2:12][CH2:13][CH2:14][Li:15].[CH:16](=[O:17])[c:18]1[cH:19][n:20][c:21]([N:27]2[CH2:28][CH2:29][N:30]([C:33](=[O:34])[O:35][C:36]([CH3:37])([CH3:38])[CH3:39])[CH2:31][CH2:32]2)[c:22]2[n:23]1[cH:24][n:25][n:26]2.[Cl:40][CH2:41][Cl:42].[cH:1]1[cH:2][cH:3][s:4][cH:5]1>>[cH:1]1[cH:2][c:3]([CH:16]([OH:17])[c:18]2[cH:19][n:20][c:21]([N:27]3[CH2:28][CH2:29][N:30]([C:33](=[O:34])[O:35][C:36]([CH3:37])([CH3:38])[CH3:39])[CH2:31][CH2:32]3)[c:22]3[n:23]2[cH:24][n:25][n:26]3)[s:4][cH:5]1
