Tert-butyl 3-oxopyrrolidine-1-carboxylate → Tert-butyl 3-hydroxy-3-(6-methoxypyridin-3-yl)pyrrolidine-1-carboxylate
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([O:8][CH3:9])[n:6][cH:7]1.[C:15](=[O:16])([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[N:22]1[CH2:23][C:24](=[O:27])[CH2:25][CH2:26]1.[CH2:10]([Li:11])[CH2:12][CH2:13][CH3:14]>>[c:2]1([C:24]2([OH:27])[CH2:23][N:22]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:26][CH2:25]2)[cH:3][cH:4][c:5]([O:8][CH3:9])[n:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-1d1ff98d957a4e6799e31b558b8cbb4c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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