HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → 4-bromo-N'-(2,2-dimethylpropanoyl)benzohydrazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | 4-Bromobenzoyl chloride | HCID 68515 | — |
| Reactant | tert-Butyl carbazate | HCID 70091 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Product | 4-bromo-N'-(2,2-dimethylpropanoyl)benzohydrazide | HCID 4782693 | — |
Reaction Steps
t-Butyloxycarbonylhydrazine (1.26 g) was added portionwise to a solution of 4-bromobenzoyl chloride (2.0 g), and DIPEA (2.37 ml) in DCM (20 ml) and the reaction stirred at room temperature for 18 hours. Ammonium chloride solution was added, the organic phase was separated, dried and the solvent evaporated under vacuum to give 4-bromo-benzoic acid N′-(2,2-dimethyl-propionyl)-hydrazide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07425555B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-8132fc3f3dc447e5b26609efe5f81896 |
| Source note | uspto-grants-2008_09 |