HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-{[5-(4-Iodophenyl)-1,3,4-oxadiazol-2-yl]methyl}piperidine → 6-Methyl-4'-(5-piperidin-1-ylmethyl-[1,3,4]oxadiazol-2-yl)biphenyl-3-carboxylic acid cyclopropylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-{[5-(4-Iodophenyl)-1,3,4-oxadiazol-2-yl]methyl}piperidine | HCID 7096895 | — |
| Reactant | N-cyclopropyl-4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide | HCID 21914577 | — |
| Product | 6-Methyl-4'-(5-piperidin-1-ylmethyl-[1,3,4]oxadiazol-2-yl)biphenyl-3-carboxylic acid cyclopropylamide | HCID 10432064 | — |
Reaction Steps
Example 13 was prepared from 1-[5-(4-iodophenyl)-[1,3,4]oxadiazol-2-ylmethyl]-piperidine (intermediate 9) and N-cyclopropyl-4-methyl-3-(4,4,5,5-tetramethyl-[1,3,2]-dioxaborolan-2-yl)benzamide (Intermediate 17).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07425555B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-cff0c77640ac402cb2e8fb83c3e78f33 |
| Source note | uspto-grants-2008_09 |