2-(4-Bromo-3-methylphenyl)-5-methyl-1,3,4-oxadiazole → HCID 58629795, compound

HRID 31451

Reaction equation

HRID 31451 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]([CH3:13])=[N:11][N:12]=2)=[CH:4][C:3]=1[CH3:14].[CH3:15][C:16]1[CH:21]=[CH:20][C:19]([NH:22][C:23]([C:25]2[CH:29]=[CH:28][S:27][CH:26]=2)=[O:24])=[CH:18][C:17]=1B1OC(C)(C)C(C)(C)O1>>[CH3:15][C:16]1[C:17]([C:2]2[CH:7]=[CH:6][C:5]([C:8]3[O:9][C:10]([CH3:13])=[N:11][N:12]=3)=[CH:4][C:3]=2[CH3:14])=[CH:18][C:19]([NH:22][C:23]([C:25]2[CH:29]=[CH:28][S:27][CH:26]=2)=[O:24])=[CH:20][CH:21]=1

Participants

3

Reactant 2

HCID 114366932-(4-Bromo-3-methylphenyl)-5-methyl-1,3,4-oxadiazoleHCID 21914662N-[4-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-3-thiophenecarboxamide2×

Product 1

HCID 58629795HCID 58629795, compound

Procedure

Example 23 was prepared using 2-(4-bromo-3-methylphenyl)-5-methyl-[1,3,4]oxadiazole and N-[4-methyl-3-(4,4,5,5,-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]thiophene-3-amide (Intermediate 27).

Workup

  1. customExample 23 was prepared

Sources & evidence

ORD record
ord-e9ac209cefc74836a49c6cf6132f5672
Source dataset
uspto-grants-2008_09
Patent number
US07425555B2

Linked notes

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