Cyclopentanone → 6,10-Dioxaspiro[4.5]dec-8-ylmethanol

HRID 31626

Reaction equation

HRID 31626 reaction equation
[OH:1][CH2:2][CH:3]([CH2:6][OH:7])[CH2:4][OH:5].[C:8]1(=O)[CH2:12][CH2:11][CH2:10][CH2:9]1>>[CH2:8]1[C:12]2([O:5][CH2:4][CH:3]([CH2:6][OH:7])[CH2:2][O:1]2)[CH2:11][CH2:10][CH2:9]1

Participants

3

Reactant 2

HCID 8452CyclopentanoneHCID 78432Trimethylolmethane

Product 1

HCID 597925846,10-Dioxaspiro[4.5]dec-8-ylmethanolYield 87%

Procedure

The same procedure as in the step (7a) of Example 7 was repeated using 2-(hydroxymethyl)-1,3-propanediol and cyclopentanone to obtain the title compound (2.8 g, yield: 87%) as yellow oil.

Sources & evidence

ORD record
ord-34ff411fa72c4faba1c55b4737b91356
Source dataset
uspto-grants-2008_09
Patent number
US07425634B2

Linked notes

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