Carbon Disulfide → HCID 178505474, compound
Reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([F:9])[CH:5]=[CH:6][C:7]=1[NH2:8].[C:10](=S)=[S:11]>CO>[F:9][C:4]1[CH:5]=[CH:6][C:7]2[NH:8][C:10]([SH:11])=[N:1][C:2]=2[CH:3]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A mixture of 3,4-diamino-1-fluorobenzene (10 g, 79.3 mmol), carbon disulfide (70 ml, 1164 mmol), and methanol (100 ml) was stirred at room temperature for 86 hours and 50 minutes. After the reaction mixture was concentrated, the residue was suspended in hexane. The resultant precipitate was collected by filtration and washed with hexane to obtain the title compound (13.1 g, yield: 98.2%) as a brown solid.
Workup
- concentrationAfter the reaction mixture was concentrated
- filtrationThe resultant precipitate was collected by filtration
- washwashed with hexane
Sources & evidence
- ORD record
- ord-31450aeabdf747aeb96b5606f43929aa
- Source dataset
- uspto-grants-2008_09
- Patent number
- US07425634B2
Reaction notes
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