Carbon Disulfide → HCID 178505474, compound

HRID 31679

Reaction equation

HRID 31679 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([F:9])[CH:5]=[CH:6][C:7]=1[NH2:8].[C:10](=S)=[S:11]>CO>[F:9][C:4]1[CH:5]=[CH:6][C:7]2[NH:8][C:10]([SH:11])=[N:1][C:2]=2[CH:3]=1

Participants

4

Reactant 2

HCID 6348Carbon DisulfideHCID 1645844-Fluorobenzene-1,2-diamine

Product 1

HCID 178505474HCID 178505474, compoundYield 98.2%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of 3,4-diamino-1-fluorobenzene (10 g, 79.3 mmol), carbon disulfide (70 ml, 1164 mmol), and methanol (100 ml) was stirred at room temperature for 86 hours and 50 minutes. After the reaction mixture was concentrated, the residue was suspended in hexane. The resultant precipitate was collected by filtration and washed with hexane to obtain the title compound (13.1 g, yield: 98.2%) as a brown solid.

Workup

  1. concentrationAfter the reaction mixture was concentrated
  2. filtrationThe resultant precipitate was collected by filtration
  3. washwashed with hexane

Sources & evidence

ORD record
ord-31450aeabdf747aeb96b5606f43929aa
Source dataset
uspto-grants-2008_09
Patent number
US07425634B2

Linked notes

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