N~1~-(Pyridin-2-yl)ethane-1,2-diamine → 2-(2-Aminoethylamino)-5-nitropyridine

HRID 31853

Reaction equation

HRID 31853 reaction equation
NCCNC1N=CC=CC=1.ClC1C=C(Cl)C=CC=1C1C(C2NC=CN=2)=CN=C([NH:30][CH2:31][CH2:32][NH:33][C:34]2[CH:39]=[CH:38][C:37]([N+:40]([O-:42])=[O:41])=[CH:36][N:35]=2)N=1>N1C=CC=CC=1>[NH2:30][CH2:31][CH2:32][NH:33][C:34]1[CH:39]=[CH:38][C:37]([N+:40]([O-:42])=[O:41])=[CH:36][N:35]=1

Participants

4

Reactant 2

HCID 410428N~1~-(Pyridin-2-yl)ethane-1,2-diamineHCID 9847557Chir-98023

Product 1

HCID 1224252-(2-Aminoethylamino)-5-nitropyridine

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

The preparation of the material 6-[(2-aminoethyl)amino]pyridine with various substitutents on the pyridine can be found in the precedures for the preparation of [4-(2,4-dichlorophenyl)-5-imidazol-2-ylpyrimidin-2-yl]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine, Example 74, and its analogues.

Sources & evidence

ORD record
ord-ca90443a31224026b610bfc2ae112ae7
Source dataset
uspto-grants-2008_09
Patent number
US07425557B2

Linked notes

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