Ethanol → N-{3-[(2-aminoimidazo[1,2-a]pyridin-6-yl)oxy]phenyl}-1,3-dimethyl-1H-pyrazole-5-carboxamide

HRID 318894

Reaction equation

HRID 318894 reaction equation
[CH3:1][n:2]1[n:3][c:4]([CH3:33])[cH:5][c:6]1[C:7](=[O:8])[NH:9][c:10]1[cH:11][c:12]([O:16][c:17]2[cH:18][cH:19][c:20]3[n:21]([cH:22]2)[cH:23][c:24]([NH:26][C:27](=[O:28])[C:29]([F:30])([F:31])[F:32])[n:25]3)[cH:13][cH:14][cH:15]1.[CH3:36][CH2:37][OH:38].[Na+:35].[OH-:34].[OH2:39]>>[CH3:1][n:2]1[n:3][c:4]([CH3:33])[cH:5][c:6]1[C:7](=[O:8])[NH:9][c:10]1[cH:11][c:12]([O:16][c:17]2[cH:18][cH:19][c:20]3[n:21]([cH:22]2)[cH:23][c:24]([NH2:26])[n:25]3)[cH:13][cH:14][cH:15]1

Participants

6

Reactant 5

HCID 702EthanolHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 577492691,3-dimethyl-N-[3-({2-[(trifluoroacetyl)amino]imidazo[1,2-a]pyridin-6-yl}oxy)phenyl]-1H-pyrazole-5-carboxamide

Product 1

HCID 57749254N-{3-[(2-aminoimidazo[1,2-a]pyridin-6-yl)oxy]phenyl}-1,3-dimethyl-1H-pyrazole-5-carboxamide

Sources & evidence

ORD record
ord-d9737258e69f4b068e30be790c98cbfa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

Loading…