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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 3191Generated: October 23, 2026

2-Pyridineethanamine → 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 36

https://huagongshe.com/en/reaction/3191

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-PyridineethanamineHCID 75919—
Reactant6-(2,6-Dichlorophenyl)-8-methyl-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-oneHCID 10736701—
Product2-aminopyrido[2,3-d]pyrimidin-7(8H)-one 36HCID 5327883—

Reaction Steps

This compound was prepared by a procedure similar to that described in Example 49 starting with 0.165 g (0.47 mmol) of 6-(2,6-dichlorophenyl)-8-methyl-2-methylsulfanyl-8H-pyrido[2,3-d]pyrimidin-7-one of Example 37 and 1.00 g (8.20 mmol) of 2-(2-aminoethyl)-pyridine yielding 0.082 g of pure product; mp 173°-174° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05733914
Source datasetuspto-grants-1998_03
ORD IDord-3a132906f38a4c07b3d4eb7a38743313
Source noteuspto-grants-1998_03