2-Chloro-5-nitropyridine → [6-(2,4-Dichlorophenyl)-5-imidazolyl(2-pyridyl)]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine

HRID 31916

Reaction equation

HRID 31916 reaction equation
ClC1C=CC([N+]([O-])=O)=CN=1.N[C:12]1[N:17]=[C:16]([NH:18][CH2:19][CH2:20][NH:21][C:22]2[CH:27]=[CH:26][C:25]([C:28]3[NH:29][CH:30]=[CH:31][N:32]=3)=[C:24]([C:33]3[CH:38]=[CH:37][C:36]([Cl:39])=[CH:35][C:34]=3[Cl:40])[N:23]=2)[CH:15]=[CH:14][C:13]=1[N+:41]([O-:43])=[O:42]>>[Cl:40][C:34]1[CH:35]=[C:36]([Cl:39])[CH:37]=[CH:38][C:33]=1[C:24]1[N:23]=[C:22]([NH:21][CH2:20][CH2:19][NH:18][C:16]2[CH:15]=[CH:14][C:13]([N+:41]([O-:43])=[O:42])=[CH:12][N:17]=2)[CH:27]=[CH:26][C:25]=1[C:28]1[NH:32][CH:31]=[CH:30][N:29]=1

Participants

3

Reactant 2

HCID 783082-Chloro-5-nitropyridineHCID 22142808{2-[(6-Amino-5-nitro(2-pyridyl))amino]ethyl}[6-(2,4-dichlorophenyl)-5-imidazolyl(2-pyridyl)]amine

Product 1

HCID 10238712[6-(2,4-Dichlorophenyl)-5-imidazolyl(2-pyridyl)]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine

Procedure

[6-(2,4-dichlorophenyl)-5-imidazolyl(2-pyridyl)]{2-[(5-nitro(2-pyridyl))amino]-ethyl}amine was prepared from 2-chloro-5-(nitro)pyridine using the general method for {2-[(6-amino-5-nitro(2-pyridyl))amino]ethyl}[6-(2,4-dichlorophenyl)-5-imidazolyl(2-pyridyl)]amine.

Sources & evidence

ORD record
ord-ddc6150e23174a238aed13c2ea2cdbb8
Source dataset
uspto-grants-2008_09
Patent number
US07425557B2

Linked notes

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