(2-Aminoethyl)[5-(trifluoromethyl)(2-pyridyl)]amine → [6-(2,4-Dichlorophenyl)-5-imidazol-2-yl(2-pyridyl)](2-{[5-(trifluoromethyl)(2-pyridyl)]amino}ethyl)amine

HRID 31919

Reaction equation

HRID 31919 reaction equation
[NH2:1][CH2:2][CH2:3][NH:4][C:5]1[CH:10]=[CH:9][C:8]([C:11]([F:14])([F:13])[F:12])=[CH:7][N:6]=1.[Cl:15][C:16]1[CH:21]=[C:20]([Cl:22])[CH:19]=[CH:18][C:17]=1[C:23]1[N:28]=[C:27](NCCNC2C=CC([N+]([O-])=O)=CN=2)[CH:26]=[CH:25][C:24]=1[C:42]1[NH:43][CH:44]=[CH:45][N:46]=1>>[Cl:15][C:16]1[CH:21]=[C:20]([Cl:22])[CH:19]=[CH:18][C:17]=1[C:23]1[N:28]=[C:27]([NH:1][CH2:2][CH2:3][NH:4][C:5]2[CH:10]=[CH:9][C:8]([C:11]([F:14])([F:12])[F:13])=[CH:7][N:6]=2)[CH:26]=[CH:25][C:24]=1[C:42]1[NH:46][CH:45]=[CH:44][N:43]=1

Participants

3

Reactant 2

HCID 2779424(2-Aminoethyl)[5-(trifluoromethyl)(2-pyridyl)]amineHCID 10238712[6-(2,4-Dichlorophenyl)-5-imidazolyl(2-pyridyl)]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine

Product 1

HCID 22142852[6-(2,4-Dichlorophenyl)-5-imidazol-2-yl(2-pyridyl)](2-{[5-(trifluoromethyl)(2-pyridyl)]amino}ethyl)amine

Procedure

[6-(2,4-dichlorophenyl)-5-imidazol-2-yl(2-pyridyl)](2-{[5-(trifluoromethyl)(2-pyridyl)]amino}ethyl)amine was prepared from (2-aminoethyl)[5-(trifluoromethyl)(2-pyridyl)]amine using the general method for [6-(2,4-dichlorophenyl)-5-imidazol-2-yl(2-pyridyl)]{2-[(5-nitro(2-pyridyl))amino]ethyl}amine.

Sources & evidence

ORD record
ord-99fe24da0ec24508ad68e9fd21ecfa71
Source dataset
uspto-grants-2008_09
Patent number
US07425557B2

Linked notes

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