Boron tribromide → 6-Hydroxy-4-(4,4,4-trifluoro-butyl)-isoquinoline

HRID 320772

Reaction equation

HRID 320772 reaction equation
[B:20]([Br:21])([Br:22])[Br:23].[Br:24][c:25]1[cH:26][c:27]2[c:28]([cH:29][cH:30][n:31][cH:32]2)[cH:33][c:34]1[OH:35].[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([CH2:13][CH2:14][CH2:15][C:16]([F:17])([F:18])[F:19])[cH:7][n:8][cH:9][c:10]2[cH:11][cH:12]1>>[OH:2][c:3]1[cH:4][c:5]2[c:6]([CH2:13][CH2:14][CH2:15][C:16]([F:17])([F:18])[F:19])[cH:7][n:8][cH:9][c:10]2[cH:11][cH:12]1

Participants

4

Reactant 3

HCID 25134Boron tribromideHCID 576470536-Methoxy-4-(4,4,4-trifluoro-butyl)-isoquinolineHCID 1358548376-Isoquinolinol, 7-bromo-

Product 1

HCID 1360928996-Hydroxy-4-(4,4,4-trifluoro-butyl)-isoquinoline

Sources & evidence

ORD record
ord-9ec03837c0e24287ab39c6df5db4405c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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