2-methoxy-N-(quinuclidin-3-yl)benzamide → N-(1-azabicyclo[2.2.2]octan-3-yl)-5-(trifluoromethyl)pyridine-2-carboxamide
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][cH:6][cH:16][c:17]1[C:18]([NH:7][CH:8]1[CH2:9][N:10]2[CH2:11][CH2:12][CH:13]1[CH2:14][CH2:15]2)=[O:19].[F:20][C:21]([c:22]1[cH:23][cH:24][c:25]([C:28](=[O:29])[OH:30])[n:26][cH:27]1)([F:31])[F:32]>>[NH:7]([CH:8]1[CH2:9][N:10]2[CH2:11][CH2:12][CH:13]1[CH2:14][CH2:15]2)[C:28]([c:25]1[cH:24][cH:23][c:22]([C:21]([F:20])([F:31])[F:32])[cH:27][n:26]1)=[O:30]Participants
3
Sources & evidence
- ORD record
- ord-9e084d1f21e8478fbea0ba9b61218b2b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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