Methanol → 4-methoxy-2-methyl-1H-pyrrolo[2,3-b]pyridine

Reaction equation

[CH3:14][OH:15].[CH3:1][O:2][c:3]1[c:4]2[c:5]([n:6][cH:7][cH:8]1)[nH:9][c:10]([CH2:12][OH:13])[cH:11]2.[OH-:16].[OH-:17].[Pd+2:18]>>[CH3:1][O:2][c:3]1[c:4]2[c:5]([n:6][cH:7][cH:8]1)[nH:9][c:10]([CH3:12])[cH:11]2

Participants

Reactant 4

HCID 887Methanol

HCID 961Hydroxide2×

HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

HCID 15885418(4-methoxy-1H-pyrrolo[2,3-b]pyridin-2-yl)methanol

Product 1

HCID 117884674-methoxy-2-methyl-1H-pyrrolo[2,3-b]pyridine

Sources & evidence

ORD record: ord-7746a511caec4ba28fe1a38099ea63b3
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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