5-(But-2-ynyloxy)pyrazine-2-carboxylic acid → N-(4'-Amino-5'-methylspiro[chroman-4,2'-imidazole]-6-yl)-5-(but-2-ynyloxy)pyrazine-2-carboxamide

HRID 321418

Reaction equation

HRID 321418 reaction equation
[CH2:1]([C:2]#[C:3][CH3:4])[O:5][c:6]1[n:7][cH:8][c:9]([C:12](=[O:13])[OH:14])[n:10][cH:11]1.[CH3:15][C:16]1=[N:30][C:19]2([N:18]=[C:17]1[NH2:31])[CH2:20][CH2:21][O:22][c:23]1[cH:24][cH:25][c:26]([NH2:29])[cH:27][c:28]12>>[CH2:1]([C:2]#[C:3][CH3:4])[O:5][c:6]1[n:7][cH:8][c:9]([C:12](=[O:14])[NH:29][c:26]2[cH:25][cH:24][c:23]3[c:28]([cH:27]2)[C:19]2([N:18]=[C:17]([NH2:31])[C:16]([CH3:15])=[N:30]2)[CH2:20][CH2:21][O:22]3)[n:10][cH:11]1

Participants

3

Reactant 2

HCID 584486775-(But-2-ynyloxy)pyrazine-2-carboxylic acidHCID 679794075'-Methylspiro[chromane-4,2'-imidazole]-4',6-diamine

Product 1

HCID 57384873N-(4'-Amino-5'-methylspiro[chroman-4,2'-imidazole]-6-yl)-5-(but-2-ynyloxy)pyrazine-2-carboxamide

Sources & evidence

ORD record
ord-90739db32e5b4929aa9cb29096330a46
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

Loading…