1-(4-Amino-3-fluorophenyl)pyridin-2-one → 5-chloro-N-[1-[1-[2-fluoro-4-(2-oxo-1-pyridinyl)anilino]-1-oxopropan-2-yl]pyrrolidin-3-yl]thiophene-2-carboxamide
Reaction equation
[CH2:1]([O:2][C:4]([CH:5]([CH3:6])[N:7]1[CH2:8][CH:9]([NH:12][C:13](=[O:14])[c:15]2[s:16][c:17]([Cl:20])[cH:18][cH:19]2)[CH2:10][CH2:11]1)=[O:21])[CH3:3].[NH2:22][c:23]1[c:24]([F:36])[cH:25][c:26](-[n:29]2[c:30](=[O:35])[cH:31][cH:32][cH:33][cH:34]2)[cH:27][cH:28]1>>[C:4]([CH:5]([CH3:6])[N:7]1[CH2:8][CH:9]([NH:12][C:13](=[O:14])[c:15]2[s:16][c:17]([Cl:20])[cH:18][cH:19]2)[CH2:10][CH2:11]1)(=[O:21])[NH:22][c:23]1[c:24]([F:36])[cH:25][c:26](-[n:29]2[c:30](=[O:35])[cH:31][cH:32][cH:33][cH:34]2)[cH:27][cH:28]1Participants
3
Sources & evidence
- ORD record
- ord-a5abe11855334536b840e126072a8b4b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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