Nitric Acid → 2,6-Dimethyl-3-nitrobenzoic acid

HRID 322008

Reaction equation

HRID 322008 reaction equation
[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([CH3:11])[C:3]=1[C:4]([OH:6])=[O:5].S(=O)(=O)(O)O.[N+:17]([O-])([OH:19])=[O:18]>>[CH3:1][C:2]1[C:10]([N+:17]([O-:19])=[O:18])=[CH:9][CH:8]=[C:7]([CH3:11])[C:3]=1[C:4]([OH:6])=[O:5]

Participants

4

Reactant 3

HCID 944Nitric AcidHCID 1118Sulfuric AcidHCID 124392,6-Dimethylbenzoic acid

Product 1

HCID 2393292,6-Dimethyl-3-nitrobenzoic acid

Conditions

Temperature
0 °C

Procedure

13.5 g (90.0 mmol) of 2,6-dimethylbenzoic acid were introduced in portions into a solution of 25 ml of conc. sulfuric acid and 25 ml of 65% strength HNO3 cooled to 0° C. After stirring at 0° C. for 1 h, the reaction mixture was poured onto ice, and the precipitate deposited was filtered off with suction and dried. 15.5 g of the title compound resulted.

Workup

  1. additionthe reaction mixture was poured onto ice
  2. filtrationthe precipitate deposited was filtered off with suction
  3. customdried

Sources & evidence

ORD record
ord-790e5437b9c847eaaa58a676fb399b9e
Source dataset
uspto-grants-2001_04
Patent number
US06211196B1

Linked notes

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