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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 322021Generated: October 24, 2026

2-(Benzyloxy)benzaldehyde → 1-(2-(Benzyloxy)phenyl)-2-propen-1-ol

https://huagongshe.com/en/reaction/322021

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Benzyloxy)benzaldehydeHCID 344784—
ReactantHCID 178418507HCID 178418507—
SolventTetrahydrofuranHCID 8028—
Product1-(2-(Benzyloxy)phenyl)-2-propen-1-olHCID 22009001—

Reaction Steps

2-(benzyloxy)benzaldehyde (5g, 23.6 mmol) was reacted with vinylmagnesium bromide in THF (90 ml) at 0 C. The reaction was quenched with 2 N HCl and the product was extracted in i-PrOAc, dried over Na2SO4 and purified by flash chromatography with EtOAc:toluene 2.5:97.5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06211197B1
Source datasetuspto-grants-2001_04
ORD IDord-a4708b1709d247f8a0d9098dd75df039
Source noteuspto-grants-2001_04