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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 323340Generated: October 25, 2026

Potassium Hydroxide → (1-(5-hydroxymethylfur-2-ylmethyl)-1H-benzoimidazole-2-yl)(piperidin-4-yl)amine

https://huagongshe.com/reaction/323340

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium HydroxideHCID 14797—
Reactant(1-(5-hydroxymethylfur-2-ylmethyl)-1H-benzimidazol-2-yl)(1-ethoxycarbonylpiperidin-4-yl)amineHCID 22009043—
SolventIsopropanolHCID 3776—
Product(1-(5-hydroxymethylfur-2-ylmethyl)-1H-benzoimidazole-2-yl)(piperidin-4-yl)amineHCID 22009201—

Reaction Steps

According to the procedure of European Patent Application 0 393 738 A1, hydrolyze (1-(5-hydroxymethylfur-2-ylmethyl)-1H-benzimidazol-2-yl)(1-ethoxycarbonylpiperidin-4-yl)amine using potassium hydroxide in isopropanol to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06211199B1
Source datasetuspto-grants-2001_04
ORD IDord-321583207b30436da2280a060f971f1c
Source noteuspto-grants-2001_04