Methanol → 4-Hydroxy-6-methyl-2-pyrone
Reaction equation
[C:1]([OH:13])(=[O:12])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]CCC(O)=O.C[OH:15]>>[OH:15][C:3]1[CH:4]=[C:5]([CH3:6])[O:12][C:1](=[O:13])[CH:2]=1Participants
3
Procedure
Similar to Example 150, 6.81 g (21.9 mmol, 73%) of a methyl ester compound was obtained as orange crystals from 6.08 g (0.0 mmol recrystallized from 3 methanol) of monomethyl ester of azelaic acid and 3.78 g (30.0 mmol) of 4-hydroxy-6-methyl-2-pyrone by recrystallization from methanol.
Sources & evidence
- ORD record
- ord-ba00ba0e1f664119be5756240563bc16
- Source dataset
- uspto-grants-2001_04
- Patent number
- US06215016B1
Reaction notes
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