4-Chlorophenyl Isocyanate → HCID 178507146, compound

HRID 32478

Reaction equation

HRID 32478 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]=[C:9]=[O:10])=[CH:4][CH:3]=1.[N-]=C=O.[NH2:14][C:15]1[N:20]([C:21]2[CH:26]=[CH:25][CH:24]=[C:23]([NH2:27])[CH:22]=2)[CH2:19][N:18]=[C:17]2[O:28][CH:29]=[CH:30][C:16]=12>>[NH2:14][C:15]1[N:20]([C:21]2[CH:26]=[CH:25][CH:24]=[C:23]([NH:27][C:9]([NH:8][C:5]3[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=3)=[O:10])[CH:22]=2)[CH2:19][N:18]=[C:17]2[O:28][CH:29]=[CH:30][C:16]=12

Participants

4

Reactant 3

HCID 76934-Chlorophenyl IsocyanateHCID 105034IsocyanateHCID 178507142HCID 178507142, compound

Product 1

HCID 178507146HCID 178507146, compound

Procedure

The compound was prepared following the procedure described Example 232(b), using 4-chlorophenyl isocyanate as the isocyanate of choice and 4-Amino-3-(3-aminophenyl)furo[2,3-d]pyrimidine (10) as the diamine of choice. MS(ES) m/e 380 [M+H]+.

Workup

  1. customThe compound was prepared

Sources & evidence

ORD record
ord-bff103b2a42047429dcc6fc22ece57c6
Source dataset
uspto-grants-2008_09
Patent number
US07427623B2

Linked notes

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