Isocyanate → HCID 178485837, compound

HRID 32492

Reaction equation

HRID 32492 reaction equation
[NH2:1][C:2]1[N:7]([C:8]2[CH:13]=[CH:12][C:11]([NH:14][CH3:15])=[CH:10][CH:9]=2)[CH2:6][N:5]=[C:4]2[S:16][CH:17]=[CH:18][C:3]=12.[F:19][C:20]1[CH:25]=[CH:24][C:23]([C:26]([F:29])([F:28])[F:27])=[CH:22][C:21]=1[N:30]=[C:31]=[O:32].[N-]=C=O>>[NH2:1][C:2]1[N:7]([C:8]2[CH:9]=[CH:10][C:11]([N:14]([C:31]([NH:30][C:21]3[CH:22]=[C:23]([C:26]([F:27])([F:29])[F:28])[CH:24]=[CH:25][C:20]=3[F:19])=[O:32])[CH3:15])=[CH:12][CH:13]=2)[CH2:6][N:5]=[C:4]2[S:16][CH:17]=[CH:18][C:3]=12

Participants

4

Reactant 3

HCID 105034IsocyanateHCID 27333802-Fluoro-5-(trifluoromethyl)phenyl isocyanateHCID 178482193HCID 178482193, compound

Product 1

HCID 178485837HCID 178485837, compound

Procedure

The compound was prepared following the procedure described in Example 429, substituting 4-amino-3-(4-(methylamino)phenyl)-thieno[2,3-d]pyrimidine as the amine and using 2-fluoro-5-trifluoromethyl-phenyl isocyanate as the isocyanate of choice. MH+=462.

Workup

  1. customThe compound was prepared

Sources & evidence

ORD record
ord-534534f0c63546078f699d706b25b0ca
Source dataset
uspto-grants-2008_09
Patent number
US07427623B2

Linked notes

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