HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Chlorophenyl)cyclopropane-1-carbonyl chloride → N-[4-(4-amino-2H-furo[2,3-d]pyrimidin-3-yl)phenyl]-1-(3-chlorophenyl)cyclopropane-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Chlorophenyl)cyclopropane-1-carbonyl chloride | HCID 24274030 | — |
| Reactant | HCID 178507147 | HCID 178507147 | — |
| Product | N-[4-(4-amino-2H-furo[2,3-d]pyrimidin-3-yl)phenyl]-1-(3-chlorophenyl)cyclopropane-1-carboxamide | HCID 178507150 | — |
Reaction Steps
The compound was prepared following the procedure described in Example 474, using 1-(3-chloro-phenyl)-cyclopropanecarbonyl chloride as the acid chloride of choice, and 4-Amino-3-(4-aminophenyl)furo[2,3-d]pyrimidine (9) as the diamine of choice. MS(ES) m/e 405 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427623B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-c025bb2240e346f0acc5227c52ec6b61 |
| Source note | uspto-grants-2008_09 |