Ethyl 2-[(4-hydroxyphenyl)methylene]-3-oxobutanoate → HCID 12657785, compound
Reaction equation
[CH2:1]([O:3][C:4](=[O:17])[C:5]([C:14](=[O:16])[CH3:15])=[CH:6][C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=1)[CH3:2].[H][H]>[Ni]>[CH2:1]([O:3][C:4](=[O:17])[CH:5]([CH2:6][C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=1)[C:14](=[O:16])[CH3:15])[CH3:2]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
According to the procedure of Liebigs Ann. Chem. (1980), 9, 1392, 2-(4-hydroxy-benzyl)-3-oxo-butyric acid ethyl ester was prepared from 2-acetyl-3-(4-hydroxy-phenyl)-acrylic acid ethyl ester, Raney-nickel, hydrogen.
Sources & evidence
- ORD record
- ord-500b5c2382654f36ad52f8cfda2f2862
- Source dataset
- uspto-grants-2001_04
- Patent number
- US06222062B1
Reaction notes
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