Ethylamine → S-Ethyl-N-acetyl-L-cysteine butylamide

HRID 325334

Reaction equation

CSC[C@@H](C(O)=O)NC(=O)C.C(N)C.[CH2:15]([S:17][CH2:18][C@@H:19]([C:24]([OH:26])=O)[NH:20][C:21](=[O:23])[CH3:22])[CH3:16].[CH2:27]([NH2:31])[CH2:28][CH2:29][CH3:30]>>[CH2:27]([NH:31][C:24](=[O:26])[C@H:19]([CH2:18][S:17][CH2:15][CH3:16])[NH:20][C:21](=[O:23])[CH3:22])[CH2:28][CH2:29][CH3:30]

Participants

Reactant 4

HCID 6341Ethylamine

HCID 8007Butylamine

HCID 147382L-Cysteine, N-acetyl-S-ethyl-

HCID 13893975N-Acetyl-S-methyl-L-cysteine

Product 1

HCID 13048737S-Ethyl-N-acetyl-L-cysteine butylamide

Procedure

S-Ethyl-N-acetyl-L-cysteine butylamide was synthesized in exactly the same manner as described in Example 14 except that the S-methyl-N-acetyl-L-cysteine and aqueous 70% ethylamine solution used in that example was replaced by S-ethyl-N-acetyl-L-cysteine and n-butylamine, respectively.

Sources & evidence

ORD record: ord-ce167042a10b45fc824caf1e824fbc90
Source dataset: uspto-grants-1984_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04440788

Linked notes

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