Methanesulfonate → 4-Methoxy-4-(3-methanesulfonyl-trans-prop-1-enyl)tetrahydropyran

Reaction equation

[CH3:1][O:2][C:3]1(/[CH:9]=[CH:10]/[CH2:11]O)[CH2:8][CH2:7][O:6][CH2:5][CH2:4]1.[S:13]([O-])(=[O:16])(=[O:15])[CH3:14]>>[CH3:1][O:2][C:3]1(/[CH:9]=[CH:10]/[CH2:11][S:13]([CH3:14])(=[O:16])=[O:15])[CH2:8][CH2:7][O:6][CH2:5][CH2:4]1

Participants

Reactant 2

HCID 85257Methanesulfonate

HCID 151990644-Methoxy-4-(3-hydroxy-trans-prop-1-enyl)tetrahydropyran

Product 1

HCID 193880264-Methoxy-4-(3-methanesulfonyl-trans-prop-1-enyl)tetrahydropyran

Procedure

4-methoxy-4-(3-hydroxy-trans-prop-1-enyl)tetrahydropyran, prepared as in Example 3, was converted to the corresponding mesylate according to the method of Crossland and Servis, J. Org. Chem., 35, 3195-3196 (1970).

Sources & evidence

ORD record: ord-386fda5ed4944274bc1fd85f94b3224b
Source dataset: uspto-grants-1993_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05268379

Reaction notes

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