Tetrabromophthalic anhydride → HCID 507315, compound

HRID 326341

Reaction equation

HRID 326341 reaction equation
[Br:1][C:2]1[C:3]([Br:15])=[C:4]([Br:14])[C:5]([Br:13])=[C:6]2[C:11](=[O:12])[O:10][C:8](=[O:9])[C:7]=12.[NH2:16][C:17]1[C:18]([F:30])=[CH:19][C:20]([Cl:29])=[C:21]([CH:28]=1)[C:22]([O:24][CH:25]([CH3:27])[CH3:26])=[O:23]>C1(C)C=CC=CC=1>[Br:13][C:5]1[C:4]([Br:14])=[C:3]([Br:15])[C:2]([Br:1])=[C:7]([C:8]([NH:16][C:17]2[CH:28]=[C:21]([C:22]([O:24][CH:25]([CH3:26])[CH3:27])=[O:23])[C:20]([Cl:29])=[CH:19][C:18]=2[F:30])=[O:9])[C:6]=1[C:11]([OH:10])=[O:12]

Participants

4

Reactant 2

HCID 12443Tetrabromophthalic anhydrideHCID 13519894Propan-2-yl 5-amino-2-chloro-4-fluorobenzoate

Product 1

HCID 507315HCID 507315, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Tetrabromophthalic anhydride (6.67 g, 0.014 mole) and 1-methylethyl 5-amino-2-chloro-4-fluorobenzoate (3.33 g, 0.014 mole) were heated to reflux with stirring in about 150 ml of toluene, then left overnight at room temperature. Filtration of the reaction mixture gave the title compound, m.p. 160°-165° C. (decomp.).

Workup

  1. temperatureto reflux
  2. filtrationFiltration of the reaction mixture

Sources & evidence

ORD record
ord-8055ea95a4f246ebb0c3db129877e53e
Source dataset
uspto-grants-1993_12
Patent number
US05268389

Linked notes

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