Tetrabromophthalic anhydride → 2,3,4,5-Tetrabromo-6-[(4-chloro-3-isopropoxycarbonyl-phenyl)carbamoyl]benzoic acid

Participants

Reaction Steps

Tetrabromophthalic anhydride (7.03 g, 0.015 mole), 1-methylethyl 5-amino-2-chlorobenzoate (3.24 g, 0.015 mole) and toluene (about 150 ml) were heated almost to reflux over 30 minutes. The reaction mixture was cooled and filtered to give the title compound, m.p. 169°-171° C. (decomp.) (8.92 g, 87% yield).

Provenance & Evidence