Phosphorus tribromide → HCID 14480083, compound
Reaction equation
[CH2:1](O)[C:2]#[C:3][CH2:4][C:5]#[C:6][CH2:7][C:8]#[C:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17].P(Br)(Br)[Br:20]>N1C=CC=CC=1.C(OCC)C>[Br:20][CH2:1][C:2]#[C:3][CH2:4][C:5]#[C:6][CH2:7][C:8]#[C:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17]Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Procedure
A mixture of 5 g of 2,5,8-heptadecatriyn-1-ol, one drop of pyridine and 2 g of phosphorus tribromide in 20 cm3 of ethyl ether is heated under reflux for 3 hours. The ether phase is then washed initially with sodium bicarbonate and then with water, and then dried over magnesium sulphate.
Workup
- temperatureis heated
- temperatureunder reflux for 3 hours
- washThe ether phase is then washed initially with sodium bicarbonate
- dry with materialwith water, and then dried over magnesium sulphate
Sources & evidence
- ORD record
- ord-17329ed6b16647f19989ba67d68f68e2
- Source dataset
- uspto-grants-1993_12
- Patent number
- US05268494
Reaction notes
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