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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 32720Generated: October 27, 2026

1-(3-Fluoro-4-piperazin-1-ylphenyl)ethanone → 1-(4-(4-(5-Bromo-2-morpholinobenzoyl)piperazin-1-yl)-3-fluorophenyl)ethanone

https://huagongshe.com/reaction/32720

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-Fluoro-4-piperazin-1-ylphenyl)ethanoneHCID 685610—
Reactant5-Bromo-2-morpholin-4-yl-benzoyl chlorideHCID 59793514—
Product1-(4-(4-(5-Bromo-2-morpholinobenzoyl)piperazin-1-yl)-3-fluorophenyl)ethanoneHCID 44580513—

Reaction Steps

The title compound was prepared according to the procedure described for example 46 from 5-Bromo-2-morpholin-4-yl-benzoyl chloride and 1-(3-Fluoro-4-piperazin-1-yl-phenyl)-ethanone (94%, yellow foam, MS (m/e): 490.3 (M+, 100%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07427612B2
Source datasetuspto-grants-2008_09
ORD IDord-d7c5da90161242f79b23e8662fcf8d54
Source noteuspto-grants-2008_09