Diethyl (dimethylamino)propanedioate → 5,6-Dihydro-7-methoxy-N,N-dimethyl-4H-imidazo(4,5,1-ij)quinolin-5-amine

HRID 327451

Reaction equation

HRID 327451 reaction equation
BrC[C:3]1[C:11]2[N:10]=[CH:9][N:8]([C:12](OC(C)(C)C)=O)[C:7]=2[CH:6]=[CH:5][CH:4]=1.[CH3:19][N:20]([CH:22](C(OCC)=O)[C:23](OCC)=O)[CH3:21].C(N(C(C(OCC)=O)[C:41](OCC)=[O:42])CCC)CC>>[CH3:41][O:42][C:5]1[CH:4]=[CH:3][C:11]2[N:10]=[CH:9][N:8]3[C:7]=2[C:6]=1[CH2:23][CH:22]([N:20]([CH3:21])[CH3:19])[CH2:12]3

Participants

4

Reactant 3

HCID 2801725Diethyl (dimethylamino)propanedioateHCID 15744964tert-Butyl 4-(bromomethyl)-1H-benzo[d]imidazole-1-carboxylateHCID 15744966Diethyl (dipropylamino)propanedioate

Product 1

HCID 700627715,6-Dihydro-7-methoxy-N,N-dimethyl-4H-imidazo(4,5,1-ij)quinolin-5-amine

Procedure

This compound was prepared by following the procedure of Example 18, but substituting t-butyl 4-(bromomethyl)-5-methoxy-1H-benzimidazole-1-carboxylate for t-butyl 4-(bromomethyl)-1H-benzimidazole-1-carboxylate and diethyl (dimethylamino)malonate for diethyl (dipropylamino)malonate.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-4915559f40824c8fa946c0507699cd4a
Source dataset
uspto-grants-1993_12
Patent number
US05273975

Linked notes

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